The webinar series will discuss adaptive platform trial (APT) designs in critical care, and review the various domains of the PRACTICAL platform trial. We welcome healthcare professionals to participate in our comprehensive webinar series designed to elevate clinical and research practices, and promote continuous learning. The webinar series will cover essential principles, trial infrastructure, strategies for implementation, insights gained, and the administration of APTs The series will introduce Bayesian statistics and adaptive trial design, explore the advantages and disadvantages of APTs, practical approaches to operationalization, best practices, valuable techniques, and challenges faced in ensuring their effective execution, and strategies for developing competitive grant applications and realistic trial budgets. The webinars will be delivered online as synchronous learning sessions, with an anticipated 50–80 attendees joining from around the world. The series will consist of lectures and applied examples, with each session engaging participants through an interactive case that includes audience voting at several points, followed by dedicated time for questions and discussion